Ovarian Cancer
Beginning of paper
Of all gynecologic malignancies, continues to have the
highest mortality and is the most difficult to diagnose. In the United States
female population, ranks fifth in absolute mortality among
cancer related deaths (13,000/yr). In most reported cases, ,
when first diagnosed is in stages III or I ....
Middle of paper
.... yet generally remains localized
within the peritoneal cavity. Tumor development has been associated with
aberrant, dysfunctional expression and/or mutation of various genes. This can
include oncogene overexpression, amplification or mutation, aberrant tumor
suppressor expression or mutation. Also, subversion of host antitumor immune
responses may play a role in the pathogenesis of cancer (Sharp, 77).
Ovarian clear cell adenocarcinoma was first described by Peham in 1899
as "hyper ....
------------------
Word count: 4156
Page count: 16 (approximately 250 words per page)