The Cystic Fibrosis Gene
Beginning of paper
Introduction:
Cystic fibrosis is an inherited autosomal recessive disease that
exerts its main effects on the digestive system and the lungs. This disease
is the most common genetic disorder among Caucasians. Cystic fibrosis
affects about one in 2,500 people, with one in twenty five being a
heteroz ....
Middle of paper
.... to first characterize
the bio-chemical defect within the gene, then to identify the mutated
protein in the gene of interest, and finally to locate the actual gene.
However, this classical approach proved to be impractical when searching
for the CF gene. To find the gene responsible for CF, the principle of
"reverse genetics" was applied. Scientists accomplished this by linking the
disease to a specific chromosome. After this linkage, they isolated the
gene of interest on the chromosome and ....
------------------
Word count: 2159
Page count: 8 (approximately 250 words per page)
