The Cystic Fibrosis Gene
Beginning of paper
Introduction:
Cystic fibrosis is an inherited autosomal recessive disease that exerts its
main effects on the digestive system and the lungs. This disease is the
most common genetic disorder among Caucasians. Cystic fibrosis affects
about one in 2,500 people, with one in twenty five being a heteroz ....
Middle of paper
.... characterize the bio-chemical
defect within the gene, then to identify the mutated protein in the gene of
interest, and finally to locate the actual gene. However, this classical
approach proved to be impractical when searching for the CF gene. To find
the gene responsible for CF, the principle of "reverse genetics" was
applied. Scientists accomplished this by linking the disease to a specific
chromosome. After this linkage, they isolated the gene of interest on the
chromosome and then tes ....
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Word count: 2157
Page count: 8 (approximately 250 words per page)